Title:
NME INHIBITORS AND METHODS OF USING NME INHIBITORS
Document Type and Number:
Japanese Patent JP2019206527
Kind Code:
A
Abstract:
To provide agents for inhibiting the functions of NME family proteins.SOLUTION: The inhibited NME family protein is NME7, NME6, or NME1. The agent is an Fab, monovalent, bivalent or IgM, bi-specific, human or humanized antibody, a peptide or peptide mimic, a natural product, a synthetic chemical, a nucleic acid, a vaccine or the like. It is administered to patients with cancer, or patients who are at risk of developing cancer.SELECTED DRAWING: None
Inventors:
CYNTHIA BAMDAD
BENOIT SMAGGHE
BENOIT SMAGGHE
Application Number:
JP2019109262A
Publication Date:
December 05, 2019
Filing Date:
June 12, 2019
Export Citation:
Assignee:
MINERVA BIOTECHNOLOGIES CORP
International Classes:
A61K45/00; A01K67/027; A61K31/7088; A61K38/17; A61K38/43; A61K39/00; A61K39/39; A61K39/395; A61P35/00; A61P37/04; A61P43/00; C07K16/18; C12Q1/68; G01N33/15; G01N33/50
Domestic Patent References:
| JP2012505636A | 2012-03-08 | |||
| JP2012529890A | 2012-11-29 |
Foreign References:
| US20120156246A1 | 2012-06-21 | |||
| US20090092603A1 | 2009-04-09 | |||
| WO2008070171A2 | 2008-06-12 | |||
| WO2012154759A2 | 2012-11-15 |
Other References:
BREAST CANCER RES. TREAT., vol. 118, no. 1, JPN6018001785, 2009, pages 113 - 124, ISSN: 0004456451
CELL STRUCT. FUNCT., vol. 35, no. 1, JPN6018001786, 2010, pages 23 - 30, ISSN: 0004456452
CANCER RES., vol. Vol. 70, No. 8 Suppl., JPN6018001783, 2010, pages 3866, ISSN: 0004456448
STEM CELLS, vol. 30, JPN6018001784, 2012, pages 2199 - 2211, ISSN: 0004456449
MOLECULAR BIOLOGY OF THE CELL, vol. 22, JPN6020025382, 2011, pages 1104 - 1119, ISSN: 0004456450
CELL STRUCT. FUNCT., vol. 35, no. 1, JPN6018001786, 2010, pages 23 - 30, ISSN: 0004456452
CANCER RES., vol. Vol. 70, No. 8 Suppl., JPN6018001783, 2010, pages 3866, ISSN: 0004456448
STEM CELLS, vol. 30, JPN6018001784, 2012, pages 2199 - 2211, ISSN: 0004456449
MOLECULAR BIOLOGY OF THE CELL, vol. 22, JPN6020025382, 2011, pages 1104 - 1119, ISSN: 0004456450
Attorney, Agent or Firm:
Takashi Shoji