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Title:
ＭＥＴ抗体薬物複合体
Document Type and Number:
Japanese Patent JP2019536780
Kind Code:
A
Abstract:
ＭＥＴ発現腫瘍細胞に結合し、それを死滅させ、ＭＥＴ発現がんの治療に有効である抗体−薬物複合体（ＡＤＣ）が提供される。また、そのようなＡＤＣを生成するための新規な化合物およびＭＥＴ抗体を複合体化する方法も提供される。

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Inventors:
Fen, Ekin
Hip skin, Philip Arthur
Re, Ren Hoa
Liu, Rin
Wilson, Takako
Robleski, Aaron David
Application Number:
JP2019527525A
Publication Date:
December 19, 2019
Filing Date:
November 17, 2017
Export Citation:
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Assignee:
Eli Lilly and Company
International Classes:
C07K16/28; A61K38/07; A61K47/68; A61P35/00
Domestic Patent References:
JP2009501800A2009-01-22
JP2012509881A2012-04-26
JP2014519492A2014-08-14
Foreign References:
WO2016094455A12016-06-16
Other References:
BIOCONJUGATE CHEM., vol. 26, JPN6020015550, 2015, pages 2233 - 2242, ISSN: 0004444325
JOURNAL OF CLINICAL ONCOLOGY, vol. Vol.34, No.15, suppl.2510, JPN6020015551, 20 May 2016 (2016-05-20), ISSN: 0004444326
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Norio Omori
Noriki Mitsuhashi
Yasuhito Suzuki



 
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