Title:
PROCESSES FOR PREPARING 4-METHYL-5-NONANONE AND 4-METHYL-5-NONANOL
Document Type and Number:
Japanese Patent JP2020100618
Kind Code:
A
Abstract:
To provide processes for preparing 4-methyl-5-nonanone and 4-methyl-5-nonanol with economical efficiency.SOLUTION: The present invention provides a process for preparing 4-methyl-5-nonanone comprising at least a step of subjecting 2-methylpentanoic anhydride of the following formula (1) and an n-butyl nucleophilic reagent of the following general formula (2) (in which M represents Li, MgZ1, or ZnZ1, wherein Z1 represents a halogen atom or an n-butyl group) to a nucleophilic substitution reaction, to produce 4-methyl-5-nonanone of the following formula (3), and a process for preparing 4-methyl-5-nonanol comprising at least the preparation process as well as a step of preparing 4-methyl-5-nonanol of the following formula (5) by subjecting the 4-methyl-5-nonanone (3) obtained by the preparation process and a reducing agent to a reduction reaction.SELECTED DRAWING: None
Inventors:
MIYAKE HIROKI
KANAO TAKESHI
NAGAE YUSUKE
KANAO TAKESHI
NAGAE YUSUKE
Application Number:
JP2019224924A
Publication Date:
July 02, 2020
Filing Date:
December 12, 2019
Export Citation:
Assignee:
SHINETSU CHEMICAL CO
International Classes:
C07C45/48; C07B49/00; C07C29/143; C07C31/125; C07C49/04
Domestic Patent References:
| JP2004529954A | 2004-09-30 | |||
| JPH069364A | 1994-01-18 |
Other References:
CHI-HIEN DANG ET AL: "A facile synthesis of racemic aggregation pheromones of palm pests, Rhinoceros beetle and Rhynchopho", ARKIVOC, vol. part V, JPN7022005077, 16 October 2017 (2017-10-16), pages 187 - 195, ISSN: 0004917295
K.MARUOKA ET AL.: "Methylaluminum bis(4-bromo-2,6-di-tert-butylphenoxide) as a Key reagent for effecting primary α-alk", J.AM.CHEM.SOC., vol. 114, JPN6022003107, 1992, pages 4422 - 4423, XP000271324, ISSN: 0004917296, DOI: 10.1021/ja00037a070
K.MARUOKA ET AL.: "Methylaluminum bis(4-bromo-2,6-di-tert-butylphenoxide) as a Key reagent for effecting primary α-alk", J.AM.CHEM.SOC., vol. 114, JPN6022003107, 1992, pages 4422 - 4423, XP000271324, ISSN: 0004917296, DOI: 10.1021/ja00037a070
Attorney, Agent or Firm:
Mitsuo Matsui
Hiroshi Murakami
Yukari Kato
Hidefumi Kawamura
Hiroshi Murakami
Yukari Kato
Hidefumi Kawamura