Title:
免疫応答の抗原特異的リダイレクターとしてのキメラウイルス様粒子およびその使用
Document Type and Number:
Japanese Patent JP2020524710
Kind Code:
A
Abstract:
本発明は、パピローマウイルス(PV)L1タンパク質またはL1/L2タンパク質を含むポリペプチドおよびヒト病原体由来のCD8+T細胞エピトープを含む標的ペプチドから組み立てられたキメラウイルス様粒子(VLP)に関する。本発明はまた、免疫応答の抗原特異的リダイレクターとしてキメラVLPを使用する方法に関する。【選択図】図1
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Inventors:
Wang, Joshua Weiyuan
Ignavat, Nata
Ignavat, Nata
Application Number:
JP2020520192A
Publication Date:
August 20, 2020
Filing Date:
June 21, 2018
Export Citation:
Assignee:
Pasovacs LLC
International Classes:
C07K14/01; A61K39/12; A61K39/385; A61K39/395; A61K45/00; A61K47/64; A61P35/00; A61P35/04; A61P43/00
Domestic Patent References:
JPH10506796A | 1998-07-07 |
Foreign References:
CN102153656A | 2011-08-17 | |||
WO1999050424A2 | 1999-10-07 | |||
US20100260792A1 | 2010-10-14 | |||
US20140050753A1 | 2014-02-20 | |||
US20100092504A1 | 2010-04-15 | |||
WO2016112921A1 | 2016-07-21 | |||
US20050142115A1 | 2005-06-30 |
Other References:
HUBER, B., ET AL.: ""Chimeric L2-based virus-like particle (VLP) vaccines targeting cutaneous human papillomaviruses (HP", PLOS ONE, vol. 12, no. 1, JPN6022025941, 5 January 2017 (2017-01-05), pages 0169533 - 1, ISSN: 0004812775
PLUMMER, E.M., ET AL.: ""Viral nanoparticles and virus-like particles: platforms for contemporary vaccine design."", WIRES NANOMEDICINE AND NANOBIOTECHNOLOGY, vol. 3, no. 2, JPN6022025942, 24 September 2010 (2010-09-24), pages 174 - 196, XP055249313, ISSN: 0004812776, DOI: 10.1002/wnan.119
PLUMMER, E.M., ET AL.: ""Viral nanoparticles and virus-like particles: platforms for contemporary vaccine design."", WIRES NANOMEDICINE AND NANOBIOTECHNOLOGY, vol. 3, no. 2, JPN6022025942, 24 September 2010 (2010-09-24), pages 174 - 196, XP055249313, ISSN: 0004812776, DOI: 10.1002/wnan.119
Attorney, Agent or Firm:
Ryoichi Takaoka
Nao Oda
Akiyo Iwahori
Kaoru Takahashi
Nao Oda
Akiyo Iwahori
Kaoru Takahashi