Title:
SYNERGISTIC COMPOSITION INCLUDING (R)-DIMIRACETAM(1) AND (S)-DIMIRACETAM(2) AT NON-RACEMIC RATIO
Document Type and Number:
Japanese Patent JP2021073171
Kind Code:
A
Abstract:
To provide a composition for inhibiting [3H]-D-asparagine acid isolation from a rat spinal cord synaptosome initiated by NMDA+glycine.SOLUTION: The invention relates to enantiomer of a certain ratio of 3, 6, 7, 7a-tetrahydro-1H-pyrrolo(1,5-a)imidazole-2,5-dione and a pharmaceutically acceptable solvent or a composition of co-crystal thereof, a pharmaceutical composition including the composition, use of the pharmaceutical composition as a medicament, and use of the composition or the pharmaceutical composition for treating or preventing a disease or disorder selected from: preferably, and typically, peripheral sensory nerve disorder, preferably, peripheral nerve disorder pain; stroke; depression; or cognition disorder.SELECTED DRAWING: None
Inventors:
MICHAEL SCHERZ
CARLO FARINA
CARLO FARINA
Application Number:
JP2020202501A
Publication Date:
May 13, 2021
Filing Date:
December 07, 2020
Export Citation:
Assignee:
METYS PHARMACEUTICALS AG
International Classes:
A61K31/4188; A61K31/337; A61K31/7068; A61K31/708; A61K45/00; A61P25/02; A61P31/12; A61P35/00
Domestic Patent References:
| JP6810983B2 | 2021-01-13 |
Foreign References:
| WO1993009120A1 | 1993-05-13 | |||
| WO2008125674A1 | 2008-10-23 | |||
| WO2012055057A1 | 2012-05-03 | |||
| WO2015010217A1 | 2015-01-29 | |||
| WO2000032558A1 | 2000-06-08 |
Attorney, Agent or Firm:
Shinichiro Tanaka
▲吉▼田 和彦
Hiroyuki Suda
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Yasushi Sasaki
▲吉▼田 和彦
Hiroyuki Suda
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Yasushi Sasaki