Title:
NOVEL LIPIDS AND COMPOSITIONS FOR DELIVERY OF THERAPEUTICS
Document Type and Number:
Japanese Patent JP2021098718
Kind Code:
A
Abstract:
To provide lipid-therapeutic nucleic acid compositions that are suitable for general therapeutic use.SOLUTION: The present invention provides novel cationic lipids, and lipid particles comprising the same. These lipid particles may further comprise an active agent and be used according to related methods of the invention to deliver the active agent to a cell.SELECTED DRAWING: None
Inventors:
MUTHIAH MANOHARAN
KALLANTHOTTATHIL G RAJEEV
DAVID BUTLER
NARAYANANNAIR K JAYAPRAKASH
MUTHUSAMY JAYARAMAN
LAXMAN ELTEPU
KALLANTHOTTATHIL G RAJEEV
DAVID BUTLER
NARAYANANNAIR K JAYAPRAKASH
MUTHUSAMY JAYARAMAN
LAXMAN ELTEPU
Application Number:
JP2021032517A
Publication Date:
July 01, 2021
Filing Date:
March 02, 2021
Export Citation:
Assignee:
TEKMIRA PHARMACEUTICALS CORP
International Classes:
A61K47/22; A61K9/14; A61K31/7088; A61K31/7105; A61K47/44; A61K48/00; A61P37/04; A61P43/00; C07D317/28; C07D317/44; C07D317/46; C07D317/72; C07D405/12; C07D491/056; C07D491/113; C07D493/04; C12N15/12; C12N15/88
Domestic Patent References:
| JP2008530215A | 2008-08-07 |
Foreign References:
| US5491152A | 1996-02-13 |
Other References:
Ｊ．ＡＭ．ＣＨＥＭ．ＳＯＣ．, vol. １２６（１）, JPN7014000331, 2004, pages 187 - 193, ISSN: 0004758792
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Ｊ．ＡＭ．ＣＨＥＭ．ＳＯＣ．, vol. １２０（１６）, JPN7014000330, 1998, pages 4017 - 4018, ISSN: 0004758793
Ｊ．ＯＲＧ．ＣＨＥＭ．, vol. ７２（１７）, JPN7014000329, 2007, pages 6591 - 6594, ISSN: 0004758794
Ｊ．ＯＲＧ．ＣＨＥＭ．, vol. ７２（８）, JPN7014000328, 2007, pages 3155 - 3157, ISSN: 0004758795
PREPRINTS, vol. Vol.35(2), JPN6016039465, 1990, pages 265 - 271, ISSN: 0004758796
TETRAHEDRON ASYMMETRY, vol. Vol.17(17), JPN6016039466, 2006, pages 2465 - 2467, ISSN: 0004758797
JOURNAL OF ORGANOMETALLIC CHEMISTRY, vol. Vol.689(2), JPN6016039468, 2004, pages 326 - 331, ISSN: 0004758798
LANGMUIR, vol. Vol.7(9), JPN6016039471, 1991, pages 1935 - 1943, ISSN: 0004758799
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. Vol.110(15), JPN6016039473, 1988, pages 5123 - 5129, ISSN: 0004758800
JOURNAL OF THE AMERICAN OIL CHEMICAL SOCIETY, vol. Vol.64(11), JPN6016039475, 1987, pages 1550 - 1551, ISSN: 0004758801
Ｊ．ＡＭ．ＣＨＥＭ．ＳＯＣ．, vol. １２０（１６）, JPN7014000330, 1998, pages 4017 - 4018, ISSN: 0004758793
Ｊ．ＯＲＧ．ＣＨＥＭ．, vol. ７２（１７）, JPN7014000329, 2007, pages 6591 - 6594, ISSN: 0004758794
Ｊ．ＯＲＧ．ＣＨＥＭ．, vol. ７２（８）, JPN7014000328, 2007, pages 3155 - 3157, ISSN: 0004758795
PREPRINTS, vol. Vol.35(2), JPN6016039465, 1990, pages 265 - 271, ISSN: 0004758796
TETRAHEDRON ASYMMETRY, vol. Vol.17(17), JPN6016039466, 2006, pages 2465 - 2467, ISSN: 0004758797
JOURNAL OF ORGANOMETALLIC CHEMISTRY, vol. Vol.689(2), JPN6016039468, 2004, pages 326 - 331, ISSN: 0004758798
LANGMUIR, vol. Vol.7(9), JPN6016039471, 1991, pages 1935 - 1943, ISSN: 0004758799
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mitsuhiro
Tatsuhiko Abe
Shinya Mitsuhiro
Tatsuhiko Abe