Title:
NUUROINHIBITORY KETAMINE AND NORKETAMINE COMPOUND, DERIVATIVE THEREOF AND METHOD
Document Type and Number:
Japanese Patent JP2021120389
Kind Code:
A
Abstract:
To provide a controllable a norketamine compound and a preparation containing the same coping with an identified gap in ketamine treatment of symptoms such as pain, depression, traumatic brain injury, stroke, epilepsy, alcohol dependence or Alzheimer's disease, without causing neurotoxic (for example, psychiatric manifestation toxicity) plasma concentration.SOLUTION: There is provided a compound having a structure represented by, for example, any one of the following formulas.SELECTED DRAWING: None
More Like This:
| JPH1072415 | 3-ANILINO-2-CYCLOALKENONE DERIVATIVE |
| JP2007528400 | Substituted hydroxyethylamine-based aspartic protease inhibitor |
| WO/2006/072354 | SQUARIC ACID DERIVATIVES |
Inventors:
ALEX NIVOROZHKIN
NELSON LANDRAU
NELSON LANDRAU
Application Number:
JP2021078368A
Publication Date:
August 19, 2021
Filing Date:
May 06, 2021
Export Citation:
Assignee:
AMORSA THERAPEUTICS INC
International Classes:
C07C225/20; A61K9/20; A61K9/48; A61K31/135; A61K47/04; A61K47/32; A61K47/34; A61K47/36; A61K47/44; A61P25/02; A61P25/22; A61P25/24; A61P25/28
Other References:
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 21, no. 19, JPN6019032842, 2011, pages 5719 - 5721, ISSN: 0004986179
EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 333, no. 1, JPN6019032843, 1997, pages 99 - 104, ISSN: 0004986180
JOURNAL OF MEDICINAL CHEMISTRY, vol. 29, no. 11, JPN6019032844, 1986, pages 2396 - 2399, ISSN: 0004986181
JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 74, no. 4, JPN6019032845, 1985, pages 486 - 488, ISSN: 0004986182
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, vol. 74, no. 2, JPN6019032848, 2012, pages 304 - 314, ISSN: 0004986183
JOURNAL OF ANALYTICAL TOXICOLOGY, vol. 33, no. 6, JPN6019032850, 2009, pages 310 - 321, ISSN: 0004986184
ADVANCES IN DRUG RESEARCH, vol. 14, JPN6019032855, 1985, pages 1 - 40, ISSN: 0004986185
DRUG NEWS & PERSPECTIVES, vol. 23, no. 6, JPN6019032859, 2010, pages 398 - 404, ISSN: 0004986186
EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 333, no. 1, JPN6019032843, 1997, pages 99 - 104, ISSN: 0004986180
JOURNAL OF MEDICINAL CHEMISTRY, vol. 29, no. 11, JPN6019032844, 1986, pages 2396 - 2399, ISSN: 0004986181
JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 74, no. 4, JPN6019032845, 1985, pages 486 - 488, ISSN: 0004986182
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, vol. 74, no. 2, JPN6019032848, 2012, pages 304 - 314, ISSN: 0004986183
JOURNAL OF ANALYTICAL TOXICOLOGY, vol. 33, no. 6, JPN6019032850, 2009, pages 310 - 321, ISSN: 0004986184
ADVANCES IN DRUG RESEARCH, vol. 14, JPN6019032855, 1985, pages 1 - 40, ISSN: 0004986185
DRUG NEWS & PERSPECTIVES, vol. 23, no. 6, JPN6019032859, 2010, pages 398 - 404, ISSN: 0004986186
Attorney, Agent or Firm:
Takuro Saeki
Nakamura Tadashi Exhibition
Yuko Saeki
Nakamura Tadashi Exhibition
Yuko Saeki