【発明の名称】新規のインダン誘導体、その製造方法及び薬剤としてのその使用

Japanese Patent JP2512314

B2

A compound selected from the group consisting of all enantiomeric and diastereoisomeric forms possible of compounds of the formula I wherein X is selected from the group consisting of hydrogen, halogen, and alkyl and alkoxy of 1 to 5 carbon atoms, R1 and R2 are individually selected from the group consisting of hydrogen and alkyl of 1 to 5 carbon atoms, one of A and B being and the other being R is hydrogen or alkyl of 1 to 5 carbon atoms, Z is -(CH2)n- or branched alkylene of 2 to 8 carbon atoms, n is an integer from 0 to 5, Y is selected from the group consisting of naphthyl, indenyl, heterobicyclics and heteromonocyclic containing 5 to 6 ring members, all optionally substituted with at least one member of the group consisting of alkyl and alkoxy of 1 to 5 carbon atoms, halogen, -OH, -CF3, -NO2, -NH2, monoalkylamino and dialkylamino of 1 to 4 alkyl carbon atoms and phenyl optionally substituted with at least one member of the group consisting of halogen and alkyl and alkoxy of 1 to 4 carbon atoms, R3 and R4 are individually hydrogen or alkyl of 1 to 5 carbon atoms or taken together with the nitrogen form a heterocyclic of 5 to 6 ring members and optionally containing -O-, -S- or nitrogen in the ring and their non-toxic, pharmaceutically acceptable acid addition salts having central analgesic and antiarythmic activity among other activities.

WO/1994/003427	2-THIOINDOLES (SELENOINDOLES) AND RELATED DISULFIDES (SELENIDES) WHICH INHIBIT PROTEIN TYROSINE KINASES AND WHICH HAVE ANTITUMOR PROPERTIES
JP2005533851	Substances and methods for treating hypercholesterolemia
JP3068200	INDUSTRIAL APPLICABILITY: Substituted N- (indole-2-carbonyl-) amides and derivatives as glycogen phosphorylase inhibitors.

FURANSOWA KUREMANSU
ODEIRU RUMARUTORE
MISHERU FUORUTAN
FURANSOWAAZU DOREBARE

JP32419387A

July 03, 1996

December 23, 1987

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ROUSSEL UCLAF

C07D209/42; A61K31/165; A61K31/33; A61K31/34; A61K31/343; A61K31/38; A61K31/395; A61K31/40; A61K31/403; A61K31/404; A61K31/42; A61K31/423; A61K31/425; A61K31/428; A61K31/47; A61P3/04; A61P7/10; A61P9/00; A61P9/06; A61P9/12; A61P25/04; A61P25/06; C07C67/00; C07C209/00; C07C209/16; C07C209/60; C07C209/62; C07C211/42; C07C213/00; C07C215/44; C07C217/74; C07C231/00; C07C231/02; C07C233/11; C07C233/23; C07C233/41; C07C233/62; C07C233/65; C07C233/74; C07C233/77; C07C233/79; C07D215/14; C07D215/48; C07D235/04; C07D263/54; C07D277/64; C07D295/12; C07D295/135; C07D295/155; C07D307/79; C07D333/24; C07D333/54; C07D333/60; C07D403/12; (IPC1-7): C07C233/11; A61K31/165; A61K31/34; A61K31/40; A61K31/425; A61K31/47; C07C209/16; C07C211/42; C07C233/23; C07C233/41; C07C233/65; C07C233/74; C07C233/79; C07D209/42; C07D215/14; C07D215/48; C07D263/54; C07D277/64; C07D295/12; C07D307/79; C07D403/12

Motohiro Kurauchi (1 outside)

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