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Title:
【発明の名称】ベンズアミド誘導体
Document Type and Number:
Japanese Patent JP2520625
Kind Code:
B2
Abstract:
NEW MATERIAL:A compound expressed by formula I (A is lower alkylene; R<6> is lower alkyl; R<1>-R<5> are H, halogen, alkoxy, nitro or amino, provided that at least one of R<1> and R<5> is nitro). EXAMPLE:N-(N,N-Diethylaminoethyl)-3-chloro-2-nitrobenzamide.hydrochlor ide. USE:A drug having promoting action on movement of digestive tracts without action on central nervous systems. PREPARATION:A compound expressed by formula II or reactive derivative thereof is reacted with a compound expressed by the formula H2N-A-N(R<6>)2 in the presence of a condensing agent (e.g. N,N'-dicyclohexylcarbodiimide) in a solvent, such as THF, to afford the compound expressed by formula I.

Inventors:
ADACHI TSUTOMU
HORISAKI TOSHIO
OGAWA AKIHIKO
SAKYAMA HIDEYO
TAGAMI HIROYUKI
TAKASE OOMICHI
Application Number:
JP4566787A
Publication Date:
July 31, 1996
Filing Date:
February 27, 1987
Export Citation:
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Assignee:
TEIKOKU HORMONE MFG CO LTD
International Classes:
C07C233/78; A61K31/165; A61P1/00; A61P25/02; C07C67/00; C07C231/00; C07C235/50; C07C235/60; C07C237/34; C07C237/42; C07C237/44; C07D207/06; (IPC1-7): C07C233/78; C07C235/50; C07C237/42; C07C237/44; C07D207/06
Domestic Patent References:
JP62238253A
Other References:
【文献】米国特許3170955(US,A)