Title:
【発明の名称】テトラヒドロナフタレン誘導体
Document Type and Number:
Japanese Patent JP2776786
Kind Code:
B2
Abstract:
Tetrahydronaphthalene derivs. of formulae (Ia) and (Ib), and salts of these are new; R1 = H, Br, CN, CHO, OH, lower alkyl, lower alkenyl, lower alkynyl, lower alkoxy, aryloxy, lower aralkoxy or aryl; R2 = an opt. protected chain of up to 20 amino acids, whose N-terminal amino acid is a free or protected amino gp.; A1-A4 = a residue of an amino acid, whose alpha -C atom, when it is asymmetrical, is in the L-configuration in A1 and A2, and in the D-configuration in A3 and A4; X = O or S; Y = a gp. of formula (i) or (ii); n = 0 or 1; R3, R4 = H or lower alkyl; Z = an opt. substd. benzene, furan, thiophene, pyridine or pyrimidine ring. Certain intermediates are also claimed.
Inventors:
KURISUTEIINE ABUREHITO
ARUFURETSUDO GURIIDERU
KURAUSU MYUURAA
DANIERU OBUREHITO
ARUFURETSUDO GURIIDERU
KURAUSU MYUURAA
DANIERU OBUREHITO
Application Number:
JP3342196A
Publication Date:
July 16, 1998
Filing Date:
February 21, 1996
Export Citation:
Assignee:
EFU HOFUMAN RA ROSHU AG
International Classes:
A61K38/00; C07K1/107; C07K7/06; C07K7/08; (IPC1-7): C07K7/06; C07K1/107
Attorney, Agent or Firm:
Hajime Tsukuni (1 person outside)