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Title:
【発明の名称】グリコペプチド抗生物質
Document Type and Number:
Japanese Patent JP2854343
Kind Code:
B2
Abstract:
A82846-related glycopeptide compounds are prepared by treating an antibiotic selected from A82846 components A, B and C with trifluoroacetic acid to remove 1) the alpha -L-O-4-epi-vancosaminyl group attached to the disaccharide; 2) the ( alpha -L-O-4-epi-vancosaminyl- beta -O-glucosyl) disaccharide group or 3) both the disaccharide group and the alpha -L-O-4-epi-vancosaminyl group attached to the peptide core from these antibiotics. The compounds have antibacterial activity, especially against Gram-positive microorganisms.

Inventors:
MANYUERU DEIBONO
ROBAATO MAIKERU MOROI
RAMAKURISHUNAN NAGARAJAN
AMERIA AHORINARIA SHABERU
Application Number:
JP27478789A
Publication Date:
February 03, 1999
Filing Date:
October 19, 1989
Export Citation:
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Assignee:
IIRAI RIRII ANDO CO
International Classes:
A61P31/04; C07K1/113; C07K1/20; A61K38/00; C07K7/00; C07K7/64; C07K9/00; (IPC1-7): C07K7/00; A61K38/00; C07K9/00
Domestic Patent References:
JP6393798A
JP62174099A
JP60231698A
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)