Title:
【発明の名称】ペプチド誘導体
Document Type and Number:
Japanese Patent JP2952951
Kind Code:
B2
Abstract:
A peptide having a peptide sequence of formula (I) and containing 25 to 50 amino acid residues in total, its amide and salts thereof (I): Leu-Met-His-Asn-Leu-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Le u-His-His-Leu-Ile-Ala-Glu-Ile. These peptide derivatives exhibit a potent inhibitory activity against hPTH superior to that of conventional ones and are expected to be useful for treating metabolic diseases wherein calcium or phosphoric acid participates, such as hypercalcemia and osteoporosis, or diseases wherein PTH and PTHrP participate.
Inventors:
KANBEIRYO TATSUHIKO
MORI AKIHISA
NAKAO YOSHIHIDE
NAKAO KENICHIRO
MORI AKIHISA
NAKAO YOSHIHIDE
NAKAO KENICHIRO
Application Number:
JP9695190A
Publication Date:
September 27, 1999
Filing Date:
April 12, 1990
Export Citation:
Assignee:
MITSUBISHI KAGAKU KK
International Classes:
A61K38/22; A61K31/00; A61P3/00; A61P3/14; C07K14/635; A61K38/00; (IPC1-7): C07K14/635
Domestic Patent References:
| JP2117695A |
Attorney, Agent or Firm:
Hasegawa Moji