Title:
【発明の名称】チアゾリン誘導体
Document Type and Number:
Japanese Patent JP3079570
Kind Code:
B2
Abstract:
To provide a compound excellent in fibrinogen receptor antagonism and cell adhesion factor antagonism. A thiazoline derivative represented by general formula (I) and a salt thereof, wherein R<1> represents cyano, carbamoyl, thiocarbamoyl, morpholinothiocarbonyl, alkylthioimidoyl, -C(=NH)-NR<1><1>R<1><2> (wherein R<1><1> and R<1><2> represent each hydrogen, alkyl, alkoxycarbonyl, cycloalkyl, phenyl, substituted phenyl, aralkyl or substituted aralkyl, or alternatively R<1><1> and R<1><2> may be combined with each other to represent a monovalent heterocyclic group together with the adjacent nitrogen atom) or imidazolin-2-yl; R<2> represents alkyl or aralkyl; R<3> represents carboxy, hydroxy, alkoxycarbonyl, benzyloxycarbonyl or pyridyl-methyloxycarbonyl; and n represents an integer of 1 to 3.
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Inventors:
Masakazu Sato
Akira Manaka
Keiko Takahashi
Yutaka Kawashima
Katsuo Hatayama
Akira Manaka
Keiko Takahashi
Yutaka Kawashima
Katsuo Hatayama
Application Number:
JP50434394A
Publication Date:
August 21, 2000
Filing Date:
July 08, 1993
Export Citation:
Assignee:
Taisho Pharmaceutical Co., Ltd.
International Classes:
C07D277/56; C07D417/12; (IPC1-7): C07D277/48; C07D417/12
Attorney, Agent or Firm:
Tomizo Kitagawa