Title:
【発明の名称】9-デオキソ-9a-アザ-9a-ホモエリスロマイシンAの9a-N-(N′-カルバモイル)及び9a-N-(N′-チオカルバモイル)誘導体
Document Type and Number:
Japanese Patent JP3131546
Kind Code:
B2
Abstract:
The invention relates to 9a-N-(N'-carbamoyl) and 9a-N-(N'-thiocarbamoyl) derivatives of 9-deoxo-9a-aza-9a-homoerythromycin A, novel semisynthetic macrolide antibiotics of the azalide series, of the formula (I) wherein R represents a C1-C3 alkyl, aryl or aralkyl group and X represents O or S, and pharmaceutically acceptable addition salts thereof with inorganic or organic acids, to the intermediates and processes for the preparation thereof, to a process for the preparation of pharmaceutical compositions as well as to the use of pharmaceutical compositions in the treatment of bacterial infections.
Inventors:
Kyundojitku Nederiko
Kobleher Gabriella
Kernerick Zericho
Kobleher Gabriella
Kernerick Zericho
Application Number:
JP30394594A
Publication Date:
February 05, 2001
Filing Date:
December 07, 1994
Export Citation:
Assignee:
Priva Huarmaseu Tosca, Chemiska, Pray Lambena E Kotume Teika Industria, Deionitzko Dorstuvu
International Classes:
A61K31/33; A61K31/70; A61K31/7042; A61K31/7048; A61K31/7052; A61P31/00; A61P31/04; C07H17/00; C07H17/08; (IPC1-7): C07H17/00; A61K31/7052; A61P31/04
Attorney, Agent or Firm:
Shigeru Yagita (1 outside)