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Title:
【発明の名称】イブプロフェンの分割
Document Type and Number:
Japanese Patent JP3195346
Kind Code:
B2
Abstract:
A process for obtaining a substantially pure enantiomer of ibuprofen is described. The process utilizes first an enantiomerically enriched mixture of ibuprofen obtained from kinetic resolution, diastereomeric crystallization or asymmetric synthesis processes. This enriched mixture is dissolved in a solvent and solid racemic ibuprofen is separated, leaving a mother liquid comprising the solvent and the enriched enantiomer substantially free of the other enantiomer.

Inventors:
Starry, Glen Patrick
Application Number:
JP50221993A
Publication Date:
August 06, 2001
Filing Date:
June 16, 1992
Export Citation:
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Assignee:
Albemarle Corporation
International Classes:
C07B57/00; C07C51/43; C07C51/487; C07C57/30; (IPC1-7): C07C51/43; C07C57/30
Domestic Patent References:
JP2138237A
Attorney, Agent or Firm:
Heikichi Odashima



 
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