Title:
【発明の名称】精製形態のDNアーゼ
Document Type and Number:
Japanese Patent JP3383307
Kind Code:
B2
Abstract:
The present invention provides the identification and characterization of two components of a recombinant preparation of DNase. These components are the purified deamidated and non-deamidated human DNases. Taught herein are the separation of these components and the use of the non-deamidated species as a pharmaceutical per se, and in particular in compositions wherein the species is disclosed within a plastic vial, for use in administering to patients suffering from pulmonary distress.
Inventors:
Frenz, John
Shire, Stephen Jay
Sriukowski, Mary Bee
Shire, Stephen Jay
Sriukowski, Mary Bee
Application Number:
JP50152894A
Publication Date:
March 04, 2003
Filing Date:
May 28, 1993
Export Citation:
Assignee:
Genentech, Inc.
International Classes:
C12N15/09; A61K35/74; A61K38/45; A61K38/46; A61P11/00; C07K1/00; C07K1/18; C07K1/22; C07K4/12; C07K14/47; C12N9/16; C12N9/22; A61K38/00; (IPC1-7): C12N15/09; A61K38/45; A61P11/00; C07K1/18; C07K1/22; C07K14/47; C12N9/16
Other References:
【文献】国際公開90/7572(WO,A1)
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)