Title:
ワクチン抗原を弱めるための胸腺依存作用を提供するリポゾーム
Document Type and Number:
Japanese Patent JP3518866
Kind Code:
B2
Abstract:
The antibody response to a target antigen may be enhanced by incorporating the antigen into a liposome along with an additional constituent which contains at least one T-helper lymphocyte recognition site. The liposomes can include a wide variety of lipid materials. Both the antigen and the T-helper lymphocite recognition site containing constituent may be associated with the liposome by using hydrophobic interactions or by covalent attachment to a lipid.
Inventors:
ナタリ ガーソン
ハウアド アー．シクス
ハウアド アー．シクス
Application Number:
JP51779191A
Publication Date:
April 12, 2004
Filing Date:
July 24, 1991
Export Citation:
Assignee:
リサーチ ディベロップメント ファンデーション
International Classes:
A61K9/127; A61K31/685; A61K39/00; A61K39/39; (IPC1-7): A61K39/00; A61K9/127
Other References:
Ｎａｔｕｒｅ ３１７ ：Ｐ３５９〜３６１（１９８５）
Ｐｒｏｃ．Ｎａｔｌ．Ａｃａｄ．Ｓｃｉ．ＵＳＡ Ｎｏ８５（１９８８）ｐ１６１０〜１６１４
Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｉｍｍｕｎｏｌｏｇｙ ，１９８５，Ｖｏｌ １３４，Ｎｏ１ ，ｐｐ６１６〜６２２
Ｐｒｏｃ．Ｎａｔｌ．Ａｃａｄ．Ｓｃｉ．ＵＳＡ Ｎｏ８５（１９８８）ｐ１６１０〜１６１４
Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｉｍｍｕｎｏｌｏｇｙ ，１９８５，Ｖｏｌ １３４，Ｎｏ１ ，ｐｐ６１６〜６２２
Attorney, Agent or Firm:
佐田 守雄
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