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Title:
高等真核細胞へ外来DNAを導入するためのアデノウイルス
Document Type and Number:
Japanese Patent JP3519407
Kind Code:
B2
Abstract:
PCT No. PCT/EP94/01065 Sec. 371 Date Sep. 29, 1995 Sec. 102(e) Date Sep. 29, 1995 PCT Filed Apr. 6, 1994 PCT Pub. No. WO94/24299 PCT Pub. Date Oct. 27, 1994Viruses or cells are targeted for selective internalization into a target in vive. A molecule Specific for a receptor on the surface of the target cell is introduced onto the surface of the virus or cell. The modified virus or cell binds the receptor in vive and is internalized by the target cell. The method provides vectors for selective delivery of nucleic acids to specific cell types in vivo and a means to alter the tropism of an infectious agent.

Inventors:
ヴァーグナー エルンシュト
コッテン マシュー
Application Number:
JP52269794A
Publication Date:
April 12, 2004
Filing Date:
April 06, 1994
Export Citation:
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Assignee:
ジェネンテック インコーポレイテッド
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
International Classes:
A61K35/14; A61K35/76; A61K48/00; C12N7/00; C12N7/01; C12N15/09; C12N7/04; C12N15/86; C12N15/861; C12N15/87; (IPC1-7): C12N15/09; A61K35/14; A61K35/76; A61K48/00; C12N7/00
Attorney, Agent or Firm:
中村 稔 (外6名)