Title:
ビタミンD系の25-カルボン酸-誘導体及びその誘導体を含有する調剤学的調整剤
Document Type and Number:
Japanese Patent JP3565847
Kind Code:
B2
Abstract:
New 25-carboxylic acid derivatives of general formula I, (I) R19 and R19a each mean a hydrogen atom or together form an exocyclic methylene group, R21 and R21a independently of one another mean a hydrogen atom, a chlorine or fluorine atom, an alkyl group with 1 to 4 carbon atoms, together a methylene group, together with quaternary carbon atom 20 mean a 3-7 membered, saturated or unsaturated carboxylic ring, Y preferably means a derivatized carboxyl radical, and the other substituents have the meanings indicated in the description as well as process for their production, are described. The new compounds have vitamin D activity as well as proliferation-inhibiting and cell-differentiating effects and are suitable for the production of pharmaceutical agents.
Inventors:
Steinmeier, Andreas
Kirsch, Geralt
Nef, Gunter
Schwarz, Katika
Tyroff-Ekat, route
Wiesinger, Herbert
Harvey, Martin
Kirsch, Geralt
Nef, Gunter
Schwarz, Katika
Tyroff-Ekat, route
Wiesinger, Herbert
Harvey, Martin
Application Number:
JP50873694A
Publication Date:
September 15, 2004
Filing Date:
October 06, 1993
Export Citation:
Assignee:
Schering Aktiengesellschaft
International Classes:
A61P3/02; A61P3/08; A61P11/00; A61P17/00; A61P31/12; A61P35/00; A61P37/00; A61P37/04; A61P43/00; C07C401/00; A61K31/59; (IPC1-7): C07C401/00; A61K31/59; A61P3/02; A61P3/08; A61P11/00; A61P17/00; A61P31/12; A61P35/00; A61P37/00; A61P37/04; A61P43/00
Domestic Patent References:
| JP55501100A | ||||
| JP54128557A | ||||
| JP4506351A | ||||
| JP4506965A | ||||
| JP7502499A |
Attorney, Agent or Firm:
Toshio Yano
Toshiomi Yamazaki
Takuya Kuno
Reinhard Einsel
Toshiomi Yamazaki
Takuya Kuno
Reinhard Einsel