Title:
アルツハイマー病を治療できる物質のスクリーニング方法
Document Type and Number:
Japanese Patent JP3574432
Kind Code:
B2
Abstract:
Model systems of Alzheimer's disease comprise a DNA sequence encoding an amyloid precursor protein (APP) isoform or fragment that has an amino acid substitution. The substituted amino acid may be other than valine at the amino acid position corresponding to amino acid residue position 717 of APP770. Methods of determining genetic predisposition to Alzheimer's disease are also disclosed.
Inventors:
James Haserov
Gourty, Alison Marie
Rotek Besloten Fennaught Shap
Malan, Michael Joan
Zacco Salam F
Gourty, Alison Marie
Rotek Besloten Fennaught Shap
Malan, Michael Joan
Zacco Salam F
Application Number:
JP2001397308A
Publication Date:
October 06, 2004
Filing Date:
December 27, 2001
Export Citation:
Assignee:
Elan Pharmaceuticals,Inc.
International Classes:
A61K38/00; A01K67/00; A01K67/027; A61P25/28; C07K14/00; C07K14/47; C07K14/575; C07K16/00; C12N1/21; C12N5/10; C12N15/00; C12N15/09; C12N15/12; C12N15/85; C12P21/02; C12Q1/02; C12Q1/68; G01N33/15; G01N33/50; G01N33/53; (IPC1-7): C12Q1/02; C12N15/09; C12Q1/68; G01N33/15; G01N33/50
Domestic Patent References:
| JP6504441A |
Attorney, Agent or Firm:
Mikio Hatta