Title:
アミロイド―βペプチド(x―≧41)の生産を変更する能力についての化合物のスクリーニング
Document Type and Number:
Japanese Patent JP3694033
Kind Code:
B2
Abstract:
This invention provides methods of screening compounds for their ability to alter the production of Aβ(x≧41) alone or in combination with Aβ(x≰40). The methods involve administering compounds to cells, specifically measuring the amounts of Aβ(x≰40) and Aβ(x≧41) produced by the cells, and comparing these amounts to that produced by the cells without administration of the compounds.
Inventors:
Martin, Citron
Selco, Dennis Jay.
Subert, Peter A.
Schenck, Dale
Selco, Dennis Jay.
Subert, Peter A.
Schenck, Dale
Application Number:
JP50331698A
Publication Date:
September 14, 2005
Filing Date:
June 18, 1997
Export Citation:
Assignee:
Athena Neurosciences, Incorporated
Brigham and Women's Hospital
Brigham and Women's Hospital
International Classes:
A01K67/027; C07K14/47; C07K16/18; C12N15/09; C12P21/02; G01N33/15; G01N33/50; G01N33/53; G01N33/68; A61K38/00; C12R1/91; (IPC1-7): G01N33/50; G01N33/15; G01N33/53
Domestic Patent References:
| JP5502368A | ||||
| JP8502587A |
Foreign References:
| WO1994001772A1 | ||||
| WO1993016101A1 | ||||
| WO1996015452A1 |
Other References:
Neuron, 1994年,Vol.13, p45-53
Attorney, Agent or Firm:
Takashi Ishida
Fukumoto product
Masaya Nishiyama
Higuchi Souji
Fukumoto product
Masaya Nishiyama
Higuchi Souji