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Title:
有機溶媒を用いて処理したポリペプチドの賦形剤安定化
Document Type and Number:
Japanese Patent JP3698721
Kind Code:
B2
Abstract:
PCT No. PCT/US94/01666 Sec. 371 Date Apr. 8, 1994 Sec. 102(e) Date Apr. 8, 1994 PCT Filed Feb. 17, 1994 PCT Pub. No. WO94/19020 PCT Pub. Date Sep. 1, 1994Methods for excipient stabilization of dry or aqueous polypeptides treated with organic solvents are disclosed, wherein the polypeptide is admixed with trehalose, a polyol having a molecular weight less than about 70,000 kD.

Inventors:
Jeffrey Elle, Cleland
Jones, Andrew Jay S
Application Number:
JP51910094A
Publication Date:
September 21, 2005
Filing Date:
February 17, 1994
Export Citation:
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Assignee:
Genentech Incorporated
International Classes:
A61K9/08; A61K9/14; A61K9/16; A61K9/22; A61K9/50; A61K38/00; A61K38/21; A61K38/23; A61K38/27; A61K47/10; A61K47/26; A61K47/34; (IPC1-7): A61K38/00; A61K9/50; A61K38/21; A61K38/27; A61K47/26; A61K47/34
Domestic Patent References:
JP63002930A
JP63502592A
JP63233926A
JP6145046A
Attorney, Agent or Firm:
Aoyama Aoi
Kyousei Tamura
Toshio Ueda