Title:
非水性結腸下剤処方物
Document Type and Number:
Japanese Patent JP3706147
Kind Code:
B2
Abstract:
Orally administered colonic purgative formulations and methods of its use for effecting partial or complete purgation of the colon in mammals, the formulations consisting of non-aqueous admixtures of a purgative salt selected from the group consisting of Mg3(PO4)2, MgHPO4, Mg(H2PO4)2, MgSO4, MgCl2, Na2SO4, sodium tartrate, potassium tartrate, magnesium tartrate and mixtures, thereof, administered in tablet or capsule form in purgative effective concentrations. Preferred embodiments make use of at least one or more magnesium phosphate salts, more preferably dibasic magnesium phosphate; other preferred embodiments include the addition of binders, dispersants and buffers which do not adversely affect osmolality or effectiveness of the purgative formulations.
Inventors:
Jacob, Leonard S.
Williams, Taffy Jay.
Cler, Robert Dee.
Aron Chick, Craig A.
Williams, Taffy Jay.
Cler, Robert Dee.
Aron Chick, Craig A.
Application Number:
JP54189598A
Publication Date:
October 12, 2005
Filing Date:
March 30, 1998
Export Citation:
Assignee:
Inkin Pharmaceutical Company, Inc.
International Classes:
A61K9/20; A61K9/48; A61K31/00; A61K31/12; A61K31/122; A61K31/19; A61K31/194; A61K31/235; A61K33/04; A61K33/06; A61K33/08; A61K33/10; A61K33/14; A61K33/42; A61P1/00; A61P1/10; (IPC1-7): A61K9/20; A61K9/48; A61K31/191; A61K31/194; A61K33/04; A61K33/06; A61K33/08; A61K33/10; A61K33/14; A61K33/42; A61P1/10
Domestic Patent References:
| JP515319A |
Foreign References:
| WO1996040078A1 |
Other References:
Annals of Clinical Research, 1974, Vol.6, No.1, p.19-24
GOODMAN and GILMAN’s The Pharmacological Basis of Therapeutics(6th Ed.). 1980, pp.1002-1005
GOODMAN and GILMAN’s The Pharmacological Basis of Therapeutics(6th Ed.). 1980, pp.1002-1005
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita