Title:
ヒアルロン酸の生産方法及び手段
Document Type and Number:
Japanese Patent JP3720361
Kind Code:
B2
Abstract:
Isolated strains of supercapsulated streptococci band at a density of no greater than 1.03 g/cm3 in a Percoll gradient and are capable of producing hyaluronic acid with molecular weight exceeding 6 million Da. Methods of producing high molecular weight hyaluronic acid employ a supercapsulated strain of streptococcus which bands at a density of no greater than 1.03 g/cm3 in a Percoll gradient. Methods of selecting streptococcus strains capable of producing hyaluronic acid with a molecular weight exceeding 6 million Da comprise, inter alia, cultivating supercapsulated strains of streptococci which band at a density of no greater than 1.03 g/cm3 in a Percoll gradient.
Inventors:
Stall, stainless
Application Number:
JP50073796A
Publication Date:
November 24, 2005
Filing Date:
May 24, 1995
Export Citation:
Assignee:
Pharmacia Arbe
International Classes:
C08B37/08; C12N1/20; C12N1/21; C12P19/26; C12R1/46; (IPC1-7): C12P19/26; C12N1/20
Domestic Patent References:
| JP2167301A | ||||
| JP64067196A | ||||
| JP62501471A | ||||
| JP3503905A |
Attorney, Agent or Firm:
Yoshio Kawaguchi