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Title:
インシュリン依存性糖尿病(IDDM)患者に作用する免疫反応および免疫治療分子
Document Type and Number:
Japanese Patent JP3778936
Kind Code:
B2
Abstract:
The present invention relates generally to molecules such as peptides, polypeptides and proteins which interact immunologically with antibodies or T-cells in subjects having pre-clinical or clinical Insulin-Dependent Diabetes Mellitus (IDDM). These molecules are preferentially immunoreactive to T-cells in subjects having pre-clinical or clinical IDDM and are useful in the development of diagnostic, therapeutic and prophylactic agents for IDDM.

Inventors:
Harrison, Leonard
Honeyman, Margo
Rudi, George
Lou, Andrew
Application Number:
JP52523896A
Publication Date:
May 24, 2006
Filing Date:
February 20, 1996
Export Citation:
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Assignee:
AMRAD POERATIONS PTY.LTD.
International Classes:
C07K7/08; G01N33/53; A61K38/00; A61P3/08; A61P3/10; C07K14/47; C07K14/62; C12N9/88; C12Q1/02; G01N33/564; G01N33/74
Domestic Patent References:
JP61033198A
JP5503220A
JP10505821A
JP10506098A
JP6505385A
JP8504406A
JP6508030A
JP9503387A
Foreign References:
US5547847
Other References:
MOLECULAR MEDICINE, 1995年,1(6), 625-33
J Immunology, 1994年 3月 1日,152(5), 2279-88
J Immunology, 2002年,169(5), 2436-43
J Immunology, 2001年,167(9), 4926-35
DIABETES, 1995年 2月,44, 216-20
Eur. J. Biochem., 1993年,212, 597-603
Attorney, Agent or Firm:
Aoyama Aoi
Kyousei Tamura
Toshio Ueda