Title:
HDLコレステロールレベルを増大する方法
Document Type and Number:
Japanese Patent JP3910635
Kind Code:
B2
Abstract:
The present invention provides a method for increasing HDL cholesterol in a mammal by stimulating an immune response that inhibits the function of CETP. Such an immune response can be induced by immunizing with CETP or fragments of CETP (together termed "CETP Peptides") which contain an epitope capable of stimulating such a response. The peptides can be conjugated to a carrier, such as KLH or ovalbumin, in order to increase immunogenicity. Adjuvants can also be administered.
Inventors:
Ku, Deborah Wai.
Brostov, Stephen W..
Carlo, Dennis Jay.
Brostov, Stephen W..
Carlo, Dennis Jay.
Application Number:
JP50153397A
Publication Date:
April 25, 2007
Filing Date:
June 05, 1996
Export Citation:
Assignee:
Avant Immunotherapeutics, Incorporated
International Classes:
A61K38/00; A61K39/00; A61K39/385; A61P3/06; A61P9/00; C07K14/47
Domestic Patent References:
| JP61140553A | ||||
| JP5148196A |
Other References:
Journal of Lipid Research, 1994年,Volume 35, 1634-1645
The Journal of Biological Chemistry, 1989年,Vol. 264, 14318-14326
The Journal of Biological Chemistry, 1989年,Vol. 264, 14318-14326
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita