Title:
芳香族化合物および該化合物を含有する製薬学的組成物
Document Type and Number:
Japanese Patent JP3949166
Kind Code:
B2
Abstract:
Compounds of formula I useful for inhibiting the pain enhancing effects of E-type prostaglandins are disclosedwherein A is a ring system in which the -CH(R3)N(R2)B-R1 and -OR4 groups are positioned in a 1,2 relationship to one another on ring carbon atoms. B is a ring system having R1 in a 1,3 or 1,4 relationship with the -CH(R1)N(R2)- linking group. A, B, R1, R2, R3 and R4 are as defined in the specification and may be substituted. Also disclosed are pharmaceutically-acceptable salts, in vivo-hydrolysable esters and amides of compounds of formula I, pharmaceutical compositions containing such compounds, processes for preparing such compounds, and the use of such compounds as therapeutic agents.
Inventors:
Gloria Ann Brolt
Application Number:
JP50365397A
Publication Date:
July 25, 2007
Filing Date:
June 17, 1996
Export Citation:
Assignee:
AstraZeneca UK Limited
International Classes:
C07D213/74; A61K31/44; A61K31/4427; A61K31/4439; A61K31/455; A61K31/495; A61K31/50; A61P25/04; A61P29/00; A61P43/00; C07D213/63; C07D213/80; C07D237/24; C07D401/04; C07D403/04; C07D413/12; C07D417/12
Domestic Patent References:
| JP10503487A |
Attorney, Agent or Firm:
Toshio Yano
Toshiomi Yamazaki
Takuya Kuno
Toshiomi Yamazaki
Takuya Kuno