Title:
モノクローナル抗体5c8が特異的に結合するタンパク質
Document Type and Number:
Japanese Patent JP4037882
Kind Code:
B2
Abstract:
This invention provides a monoclonal antibody capable of binding to a protein which is specifically recognized by monoclonal antibody 5c8 produced by the hybridoma having ATCC Accession No. HB 10916. This invention also provides an isolated protein which is specifically recognized by monoclonal antibody 5c8 produced by the hybridoma having ATCC Accession No. HB 10916. This invention further provides an isolated nucleic acid molecule encoding a protein which is specifically recognized by monoclonal antibody 5c8 produced by the hybridoma having ATCC No. HB 10916. This invention also provides a human CD4<-> T cell leukemia cell line designated D1.1 having ATCC Accession No. CRL 10915 capable of constitutively providing cotnact-dependent helper function to B cells.
Inventors:
Seth Lederman
Leonard Chess
Michael Jay Yerin
Leonard Chess
Michael Jay Yerin
Application Number:
JP2005223497A
Publication Date:
January 23, 2008
Filing Date:
August 01, 2005
Export Citation:
Assignee:
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
International Classes:
C07K16/28; G01N33/50; A61K35/76; A61K38/00; A61K38/17; A61K39/00; A61K39/395; A61K47/48; A61K48/00; A61K49/00; A61K51/10; A61P3/10; A61P5/14; A61P7/04; A61P7/06; A61P17/06; A61P19/02; A61P21/04; A61P29/00; A61P31/14; A61P35/00; A61P35/02; A61P37/00; A61P37/02; A61P37/06; A61P37/08; A61P43/00; C07K14/47; C07K14/705; C07K14/725; C12N1/15; C12N1/19; C12N1/21; C12N5/09; C12N5/10; C12N15/02; C12N15/09; C12N15/12; C12N15/13; C12P21/02; C12P21/08; C12Q1/02; G01N33/15; G01N33/53; G01N33/566; G01N33/574; G01N33/577; C12R1/91
Domestic Patent References:
| JP7505761A |
Attorney, Agent or Firm:
Takehiko Suzue
Satoshi Kono
Makoto Nakamura
Yoshihiro Fukuhara
Toshio Shirane
Sadao Muramatsu
Ryo Hashimoto
Tetsuya Kazama
Satoshi Kono
Makoto Nakamura
Yoshihiro Fukuhara
Toshio Shirane
Sadao Muramatsu
Ryo Hashimoto
Tetsuya Kazama