Title:
β-ラクタム誘導体の製造法
Document Type and Number:
Japanese Patent JP4138911
Kind Code:
B2
Abstract:
A process for preparing a beta -lactam derivative represented by the formula (2) A-COOH wherein A is a residue of the beta -lactam derivative, the process being characterized in that a beta -lactam derivative having a protected carboxyl group which derivative is represented by the formula (1) A-COO-X wherein A is as defined above and X is a benzyl group which may have an electron-donating group as a substituent on a phenyl ring or a diphenylmethyl group which may have an electron-donating group as a substituent on a phenyl ring, is treated with aluminum halide in an aliphatic ether solvent to give the derivative of the formula (2); and that the removed group X can be recovered as X-OH for reuse.
Inventors:
Kameyama Yutaka
Application Number:
JP18441497A
Publication Date:
August 27, 2008
Filing Date:
June 24, 1997
Export Citation:
Assignee:
Otsuka Chemical Holdings Co., Ltd.
International Classes:
C07D501/04; A61K31/43; A61K31/545; A61K31/546; A61P31/04; C07D463/00; C07D463/06; C07D471/04; C07D495/04; C07D499/00; C07D499/08; C07D499/46; C07D501/00; C07D501/26; C07D501/36; C07D501/57; C07D501/59; C07D503/00; C07D505/00; A61K31/431
Domestic Patent References:
| JP52106891A | ||||
| JP61263984A | ||||
| JP61118329A | ||||
| JP61293987A |
Attorney, Agent or Firm:
Iwao Tamura