Title:
グリシン-N,N-ジ酢酸誘導体の製造方法
Document Type and Number:
Japanese Patent JP4227201
Kind Code:
B2
Abstract:
Prepn. is of glycine-N,N-diacetic acid derivs. of formula (I). R = 1-30C alkyl or 2-30C alkenyl, which can also contain, as substits., up to 5 hydroxyl gps., formyl gps., 1-4C alkoxy gps., phenoxy gps., or 1-4C alkoxycarbonyl gps., and which can be interrupted by up to 5 non-adjacent O atoms, alkoxylate groupings of formula -(CH2)k-O-(A<1>O)m-(A<2>O)n-Y in which A<1> and A<2> are 2-4C 1,2-alkylene gps., Y is H, 1-12C alkyl, phenyl or 1-4C alkoxycarbonyl and is 1, 2 or 3 and m and n are 0-50, the sum of m+n being at least 4, phenyl alkyl gps., with 1-20C atoms in the alkyl, phenyl a 5- or 6-membered (un)satd. heterocyclic ring with up to 3 heteroatoms from N, O and S which can also be benzo condensed, whereby all phenyl cores and heterocyclic rings given for R can also contain as substits. up to 3 1-4C alkyl gps., hydroxy gps., carboxyl gps., sulpho gps. or 1-4C alkoxy carbonyl gps., or a gp. of formula (II) where A is a 1-12C alkylene bridge or a chemical bond and M is H, alkali metal, alkaline earth metal, ammonium or substd. ammonium in the corresp. stoichiometric quantities. The prepn. involves reacting : (A) corresp. 2-substd. glycines or 2-substd. glycine nitriles or double glycines of formula H2N-C(COOM)H-A-C(COOM)H-NH2 (III) or double glycine nitriles of formula H2N-C(CN)H-A-C(CN)H-NH2 (IV) or precursors of the glycine derivs. given as starting materials with formaldehyde and HCN in aq. medium at a pH of 0-11, or (B) iminodiacetonitrile or iminodiacetic acid with corresp. monoaldehyde of formula R-CHO or dialdehydes of formula OHC-A-CHO and HCN in aq. medium at a pH of 0-11 and opt. subsequently saponifying the nitrile functions present. Non-purified raw material originating from the industrial synthesis of glycine derivs. or their precursors or of iminodiacetonitrile or iminodiacetic acid or mother liquors resulting during such synthesis are used as starting materials
Inventors:
Thomas grinder
Alfred Ottling
Gerold Brown
Jochen Wild
Birgit Pothof-Curl
Georg Shoe
Alfred Ottling
Gerold Brown
Jochen Wild
Birgit Pothof-Curl
Georg Shoe
Application Number:
JP12868696A
Publication Date:
February 18, 2009
Filing Date:
May 23, 1996
Export Citation:
Assignee:
BASF SE
International Classes:
C07C227/18; C07C229/16; C07C227/16; C07C227/26
Domestic Patent References:
| JP63267751A | ||||
| JP1268665A | ||||
| JP53082706A | ||||
| JP3086856A |
Foreign References:
| WO1994029421A1 |
Attorney, Agent or Firm:
Toshio Yano
Toshiomi Yamazaki
Reinhard Einsel
Toshiomi Yamazaki
Reinhard Einsel