Title:
β-アミロイドインヒビターとしてのα-(N-スルホンアミド)アセトアミド誘導体
Document Type and Number:
Japanese Patent JP4287746
Kind Code:
B2
Abstract:
There is provided a series of novel alpha-(N-sulfonamido)acetamide compounds of the Formula (I) wherein R, R1, R2 and R3 are defined herein, which are inhibitors of beta-amyloid peptide (beta-AP) production and are useful in the treatment of Alzheimer's Disease and other conditions affected by anti-amyloid activity.
Inventors:
Michael f parker
Catherine E. McElhorn
Robert a mate
Joan Jay Bronson
Yong Hwa Guy
Karl Pee Bergstrom
Lawrence Earl Marsin
John E. Macaw
Catherine E. McElhorn
Robert a mate
Joan Jay Bronson
Yong Hwa Guy
Karl Pee Bergstrom
Lawrence Earl Marsin
John E. Macaw
Application Number:
JP2003554629A
Publication Date:
July 01, 2009
Filing Date:
December 20, 2002
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
C07C311/19; A61K31/18; A61K31/192; A61K31/197; A61K31/216; A61K31/223; A61K31/24; A61K31/277; A61K31/341; A61K31/381; A61K31/40; A61K31/41; A61K31/415; A61K31/4164; A61K31/4184; A61K31/4196; A61K31/4245; A61K31/433; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4439; A61K31/445; A61K31/4453; A61K31/4525; A61K31/4545; A61K31/455; A61K31/47; A61K31/472; A61K31/495; A61K31/497; A61K31/5375; A61K31/5377; A61K31/54; A61P25/28; A61P43/00; C07C237/04; C07C237/14; C07C317/32; C07C323/49; C07C323/60; C07D207/14; C07D207/325; C07D211/14; C07D211/28; C07D211/42; C07D211/46; C07D211/58; C07D211/60; C07D213/40; C07D213/42; C07D213/61; C07D213/74; C07D213/81; C07D213/82; C07D215/06; C07D217/04; C07D217/06; C07D231/12; C07D233/64; C07D235/14; C07D249/08; C07D257/04; C07D261/08; C07D271/06; C07D271/10; C07D277/28; C07D285/01; C07D285/06; C07D285/12; C07D295/08; C07D295/12; C07D295/13; C07D295/135; C07D295/14; C07D295/18; C07D295/20; C07D307/68; C07D333/20; C07D333/28; C07D401/04; C07D405/04; C07D413/04; C07D521/00; C07D207/32; C07D235/10; C07D285/00
Domestic Patent References:
| JP2000515153A | ||||
| JP11080098A |
Foreign References:
| WO2000044716A1 | ||||
| US6313123 | ||||
| WO2000050391A1 | ||||
| WO1998009940A1 | ||||
| WO2000006561A1 |
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Yasushi Morimoto
Toshio Ueda
Nagatoshi Shinagawa
Samejima Mutsumi
Yasushi Morimoto
Toshio Ueda
Nagatoshi Shinagawa