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Title:
タキキニンアンタゴニスト
Document Type and Number:
Japanese Patent JP4306804
Kind Code:
B2
Abstract:
PCT No. PCT/EP97/07307 Sec. 371 Date Jul. 14, 1999 Sec. 102(e) Date Jul. 14, 1999 PCT Filed Dec. 29, 1997 PCT Pub. No. WO98/31704 PCT Pub. Date Jul. 23, 1998Compounds of formula (I) wherein X is -CH2-, -CO- or direct linkage, Y is -O-, -S- or -NH-, R1 is phenyl, R2=H or phenyl and R3 is H or -CH3- and their pharmaceutically acceptable salts have tachykinin antagonist activity and are useful as pharmaceuticals e.g. for the treatment of pain and migraine.

Inventors:
Walpole, Christopher Simon John
Prashad, Mahavir
Har, dennis
Application Number:
JP53360998A
Publication Date:
August 05, 2009
Filing Date:
December 29, 1997
Export Citation:
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Assignee:
NOVARTIS AG
International Classes:
A61K38/00; C07K5/078; A61P29/00; C07K7/22
Domestic Patent References:
JP4210996A
Foreign References:
WO1996018643A1
Attorney, Agent or Firm:
Aoyama Aoi
Mitsutaka Iwasaki
Shoji Nakajima