Title:
セロトニンアゴニストおよびアンタゴニストとしての置換されたピロロキノリン化合物およびピリドキノリン化合物
Document Type and Number:
Japanese Patent JP4386639
Kind Code:
B2
Abstract:
The present invention is directed to certain novel compounds represented by structural Formula (I)or pharmaceutically acceptable salt forms thereof, wherein is R<1>, R<6a>, R<6b>, R<7>, R<8>, R<9>, X, b, m, and n are described herein. The invention is also concerned with pharmaceutical formulations comprising these novel compounds as active ingredients and the use of the novel compounds and their formulations in the treatment of certain disorders. The compounds of this invention are serotonin agonists and antagonists and are useful in the control or prevention of central nervous system disorders including obesity, anxiety, depression, psychosis, schizophrenia, sleep disorders, sexual disorders, migraine, conditions associated with cephalic pain, social phobias, and gastrointestinal disorders such as dysfunction of the gastrointestinal tract motility.
More Like This:
Inventors:
John M. Febig
Ian S. Mitchell
Techie lee
Wenting Chen
Joseph Catchola
Ian S. Mitchell
Techie lee
Wenting Chen
Joseph Catchola
Application Number:
JP2002559426A
Publication Date:
December 16, 2009
Filing Date:
December 19, 2001
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
C07D471/14; A61K31/437; A61K31/4375; A61K31/4745; A61K31/553; A61P1/14; A61P3/04; A61P15/00; A61P25/00; A61P25/04; A61P25/18; A61P25/20; A61P25/22; A61P25/24; C07D209/00; C07D221/00; C07D471/16; C07D498/14; C07D498/16; C07D513/16; A61K; A61P; C07D
Domestic Patent References:
| JP4230685A |
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto