Title:
CRFアンタゴニストとしてのインダゾール誘導体
Document Type and Number:
Japanese Patent JP4401298
Kind Code:
B2
Abstract:
This invention relates to compounds which are generally CRF-1 receptor antagonists and which are represented by Formula I or Formula II: wherein R3 is optionally substituted aryl or heteroaryl, R1 and R2 are as defined in the specification; or individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts thereof. The invention further relates to processes for preparing such compounds, to pharmaceutical compositions containing such compounds, and to methods for their use as therapeutic agents.
Inventors:
Coonoer, Richard Leo
Rough Head, David Garrett
Oh Young, Cound
Rough Head, David Garrett
Oh Young, Cound
Application Number:
JP2004556171A
Publication Date:
January 20, 2010
Filing Date:
November 24, 2003
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D231/56; A61K31/416; A61K31/4439; A61P25/00; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P43/00; C07D209/44; C07D401/04
Foreign References:
| WO2002016348A1 | ||||
| WO2001058869A1 | ||||
| US6005109 | ||||
| WO2003078403A1 | ||||
| WO2003035625A1 | ||||
| WO2000027394A1 |
Other References:
Heterocycles,1992年,vol. 34, No. 1,p.p. 129-134
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda
Fumio Shinoda