Title:
神経系疾患及び癌における非定型プロテインキナーゼCアイソフォーム
Document Type and Number:
Japanese Patent JP4443418
Kind Code:
B2
Abstract:
The present invention establishes a link between altered aPKC function and nervous system disorders and cancers, such as Alzheimer's disease (AD) and neuroblastoma. Methods of using aPKC in diagnosis, drug screening and gene therapy in nervous system disorders and cancers are provided.
Inventors:
Suck Toa, Todd Charlton
Clary, John Fonda
Hernandez, Alejandro Ivan
Mira, Suzanne
Xiao, Charles
Clary, John Fonda
Hernandez, Alejandro Ivan
Mira, Suzanne
Xiao, Charles
Application Number:
JP2004550506A
Publication Date:
March 31, 2010
Filing Date:
November 03, 2003
Export Citation:
Assignee:
The Research Foundation of State University of New York
International Classes:
C12Q1/68; A61K38/45; A61K39/395; A61K48/00; A61P25/00; C07K16/40; C12N15/09; C12N15/85; C12Q1/00; C12Q1/02; C12Q1/48; C12Q1/70; G01N33/53; G01N33/567; G01N33/569; G01N33/573; G01N33/68; A61K
Other References:
Neuroscience Letters, (1998), Vol. 254, p. 29-32
J. Biol. Chem., (2001), Vol. 276, No. 13, p. 10025-10031
Molecular Brain Research, (2001), Vol. 95, p. 146-152
J. Biol. Chem., (2001), Vol. 276, No. 13, p. 10025-10031
Molecular Brain Research, (2001), Vol. 95, p. 146-152
Attorney, Agent or Firm:
Hidekazu Miyoshi