Title:
全身性紅斑性狼瘡を治療するためのペプチド
Document Type and Number:
Japanese Patent JP4459307
Kind Code:
B2
Abstract:
A method is disclosed for treating systemic lupus erythematosus in a mammalian subject, comprising administering to said subject an effective dose of at least one laminin peptide, or an analog or a derivative thereof. In one exemplary embodiment, the laminin peptide is selected from the group consisting of R38, and claimed R38 analogs and derivatives thereof including 5200, 5104, 5105, 5106, 5107, 5108, 5109, and 5110. The laminin peptides of the present invention may be prepared by known chemical synthetic methods or by biotechnological methods. Assays useful for the diagnosis of and following pathological activity course of systemic lupus erythematosus in patients suffering therefrom.
Inventors:
Napers Tech, Jacob
Application Number:
JP54532898A
Publication Date:
April 28, 2010
Filing Date:
March 20, 1998
Export Citation:
Assignee:
Hadasit Medical Research Services and Development Company Limited
International Classes:
C12N15/00; A61K38/00; A61P37/06; A61P43/00; C07K14/78; C07K16/28
Foreign References:
| WO1995022979A1 | ||||
| US5266328 | ||||
| WO1996004926A1 |
Other References:
Journal of Autoimmunity, 1995年, Vol.8, pp.279-291
J. Clin. Invest., 1994年, Vol.93, pp.1787-1797
J. Clin. Invest., 1994年, Vol.93, pp.1787-1797
Attorney, Agent or Firm:
Takehiko Suzue
Sadao Muramatsu
Ryo Hashimoto
Toshio Shirane
Sadao Muramatsu
Ryo Hashimoto
Toshio Shirane