ヒスタミンH3アンタゴニストとしての1-(4-ピペリジニル)ベンズイミダゾロン

Japanese Patent JP4563800

B2

Disclosed are novel compounds of the formula wherein R¹ is benzimidazolone derivative, M¹ and M² are optionally substituted carbon or nitrogen, R² includes optionally substituted aryl or heteroaryl, and the remaining variables are as defined in the specification, and the remaining variables are as defined in the specification; also disclosed are pharmaceutical compositions comprising the compounds of formula I and methods of treating various diseases or conditions, such as allergy, allergy-induced airway responses, and congestion (e.g., nasal congestion) using the compounds of formula I, as well as methods of treating said diseases or conditions using the compounds of formula I in combination with an H₁ receptor antagonist.

JP2006516149	N- (substituted arylmethyl) -4- (disubstituted methyl) piperidine and pyridine
JP4210754	Metal complex dendrimers and their uses

Chin, Pauline Sea.
Aslanian, Robert G.
Berlin, Michael Wye.
Voice, Christopher W.
Khao, Junghwa
Mangia Latina, Pietro
McCormick, Kevin Dee.
Mutahi, Mwangi W.
Rosenblum, Stuart Bee.
See, Nen-Yang
Solomon, Daniel M.
Tom, Wing Sea.
Zen, Chimbay

JP2004510788A

October 13, 2010

April 16, 2003

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Schering Corporation

C07D401/14; C07D487/04; A61K31/4545; A61K31/501; A61K31/506; A61K31/517; A61K31/5377; A61P1/00; A61P3/04; A61P9/00; A61P9/02; A61P11/00; A61P11/02; A61P25/00; A61P25/06; A61P25/18; A61P25/20; A61P25/28; A61P37/08; C07D405/14; C07D409/14; C07D413/14; C07D417/14; C07D471/04

JP2006206603A
JP7041465A
JP4235161A
JP8225570A
JP11513991A
JP2004509871A

WO1996013262A1
WO2001032649A1
WO2002085890A1
US5807865

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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