Title:
対流増加式薬物配給装置および使用方法
Document Type and Number:
Japanese Patent JP4574120
Kind Code:
B2
Abstract:
An implantable drug delivery system includes an infusion pump assembly (20) with a fluid outlet, a fluid delivery pathway (40) extending from the pump outlet to a target tissue site; and a controlled release material unit (30) positioned in the fluid delivery pathway to release a drug or bioactive material into the delivery pathway. The pump assembly delivers fluid as a high flow infusion flow in said pathway, entraining drug material released by the release unit and establishing a pressure gradient at the distal end of the pathway that results in convection-enhanced transport such that the released drug(s) or treatment material enter the target tissue site with enhanced penetration depth and/or concentration. The pump delivers a carrier fluid that may reside in an external or in an implanted reservoir (24), or that may be an endogenous fluid, such as plasma or CSF.
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Inventors:
William Elle Law
Alan Jay Dextrader
David Dee Konyzinsky
Alan Jay Dextrader
David Dee Konyzinsky
Application Number:
JP2003058903A
Publication Date:
November 04, 2010
Filing Date:
March 05, 2003
Export Citation:
Assignee:
Codman & Shurtleff, Inc.
International Classes:
A61M37/00; A61K9/22; A61M5/142; A61M25/00
Domestic Patent References:
| JP3178669A | ||||
| JP2000510746A | ||||
| JP2000513725A |
Foreign References:
| WO2001035928A1 |
Attorney, Agent or Firm:
Konobu Kato