Title:
抗菌・抗カビ性エーテル類
Document Type and Number:
Japanese Patent JP4610744
Kind Code:
B2
Abstract:
The present invention concerns compounds of formulathe N-oxide forms, the salts, the quaternary amines and stereochemically isomeric forms thereof, whereinD represents a tetrahydrofuran or dioxolane ring substituted with aryl and azolmethyl; -A-B- represents an optionally substituted bivalent radical of formula -N=CH-, -CH=N-, -CH=CH-, -CH2-CH2; Alk represents C1-6alkanediyl; Y represents optionally substituted C1-6alkanediyl; R1 and R2 represent hydrogen, C1-6alkyl or arylC1-6alkyl; or R1 and R2 may be taken together to form an optionally substituted heterocyclic radical selected from morpholinyl, pyrrolidinyl, piperidinyl, homopiperidinyl, piperazinyl or phthalimid-1-yl; aryl represents phenyl, naphthalenyl, 1,2,3,4-tetrahydro-naphthalenyl, indenyl or indanyl; each of said aryl groups may optionally be substituted; having broad-spectrum antifungal activity; their preparation, compositions containing them and their use as a medicine.
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Inventors:
Mail Paul, Leven
Batuks, Leo Jakobs Ziosef
Batuks, Leo Jakobs Ziosef
Application Number:
JP2000615610A
Publication Date:
January 12, 2011
Filing Date:
April 20, 2000
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP
International Classes:
C07D405/14; A61K31/496; A61P31/04; A61P31/10; C07D521/00
Domestic Patent References:
| JP10231296A |
Foreign References:
| WO1998034934A1 | ||||
| WO1999054327A1 | ||||
| EP0006711A1 |
Attorney, Agent or Firm:
Patent business corporation Odashima patent office