Title:
連続的薬剤送達システム
Document Type and Number:
Japanese Patent JP4617081
Kind Code:
B2
Abstract:
The invention relates to methods and composition for improving absorption and dissolution of active ingredients of drugs. The invention provides a method of administration of an active ingredient to a mammal through a transmucosal route that includes delivering the active ingredient to a desired site in a body of the mammal, and, sequentially, at the desired site, promoting dissolution and absorption of the active ingredient. In a preferred embodiment, the ph of the localized environment of the active ingredient is sequentially modified to promote dissolution and absorption.
Inventors:
Pacer, S. Indylan
Honts, john
Seabert, John M
Honts, john
Seabert, John M
Application Number:
JP2003511754A
Publication Date:
January 19, 2011
Filing Date:
July 10, 2002
Export Citation:
Assignee:
Cima Loves, Inc.
International Classes:
A61K9/20; A61K9/02; A61K9/22; A61K31/437; A61K31/4725; A61K31/5415; A61K47/02; A61K47/04; A61K47/12; A61K47/26; A61K47/36
Domestic Patent References:
| JP2002509872A |
Foreign References:
| WO2000066089A1 |
Attorney, Agent or Firm:
Shoichi Okuyama
Arihara Koichi
Matsushima Tetsuo
Arihara Koichi
Matsushima Tetsuo