Title:
ヒト化抗CD47抗体
Document Type and Number:
Japanese Patent JP4637749
Kind Code:
B2
Abstract:
The present invention relates to humanized antibodies binding to CD47; diabodies binding to human CD47, characterized in that a disulfide bond exists between diabody-forming fragments; genes encoding any one of said antibodies; vectors containing said genes; host cells containing said vectors; processes for preparing antibodies comprising the step of culturing said host cells; and therapeutic agents for hematological disorders comprising said antibodies.
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Inventors:
Yasufumi Kikuchi
Shinsuke Uno
Kyoko Kinoshita
Nariyuki Iijima
Nao Fukushima
Masayuki Tsuchiya
Shinsuke Uno
Kyoko Kinoshita
Nariyuki Iijima
Nao Fukushima
Masayuki Tsuchiya
Application Number:
JP2005515369A
Publication Date:
February 23, 2011
Filing Date:
November 11, 2004
Export Citation:
Assignee:
Chugai Pharmaceutical Co., Ltd.
International Classes:
C07K16/28; A61K39/395; A61P7/00; A61P7/06; A61P35/00; A61P35/02; C12N5/10; C12N15/09; C12P21/08
Domestic Patent References:
| JP4502408A | ||||
| JP8217799A | ||||
| JP11092500A |
Foreign References:
| WO1999012973A1 | ||||
| WO2000053634A1 |
Attorney, Agent or Firm:
Kazuo Shamoto
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroko Ejiri
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroko Ejiri