Title:
MDM2インヒビターとしてのシス-イミダゾリン類
Document Type and Number:
Japanese Patent JP4643570
Kind Code:
B2
Abstract:
The present invention provides compound according to formula (I) and pharmaceutically acceptable salts and esters thereof, having the designations provided herein and which inhibit the interaction of MDM2 protein with a p53-like peptide and have antiproliferative activity.
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Inventors:
Fodui, Nadé
Liu, Emily Aijun
Bu, Bin Tan
Liu, Emily Aijun
Bu, Bin Tan
Application Number:
JP2006515863A
Publication Date:
March 02, 2011
Filing Date:
June 09, 2004
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D233/22; A61K31/4164; A61K31/454; A61K31/496; A61P35/00; A61P43/00; C07D401/06; C07D403/06
Domestic Patent References:
| JP3170424A | ||||
| JP2101065A |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Masaru Nakajima
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Masaru Nakajima