Title:
短鎖のカチオン性ポリアミノ酸およびその使用
Document Type and Number:
Japanese Patent JP4655298
Kind Code:
B1
Abstract:
The present invention provides a cationic polyamino acid suitable for a carrier that can form a stable complex with a nucleic acid under a physiological condition and release the nucleic acid in cells suitably. The cationic polyamino acid can associate with a nucleic acid and includes a cationic amino acid residue having a cationic group in a side chain and a hydrophobic amino acid residue having a hydrophobic group in a side chain. The cationic polyamino acid includes 1 to 20 units of the cationic amino acid residue and is represented by the following formula (1). The meaning of each symbol in the formula is as shown in the description.
Inventors:
Yasumi Kato
Atsushi Ishii
Naoya Shibata
Tatsuyuki Hayashi
Kazunori Kataoka
Miyata Kanjiro
Nobuhiro Nishiyama
Atsushi Ishii
Naoya Shibata
Tatsuyuki Hayashi
Kazunori Kataoka
Miyata Kanjiro
Nobuhiro Nishiyama
Application Number:
JP2010037014A
Publication Date:
March 23, 2011
Filing Date:
February 23, 2010
Export Citation:
Assignee:
NanoCarrier Co., Ltd.
National University Corporation Tokyo University
National University Corporation Tokyo University
International Classes:
C08G69/48; A61K31/7105; A61K31/713; A61K47/42; A61K47/48; A61K48/00; C07K4/00
Foreign References:
| WO2009113645A1 | ||||
| WO2007099661A1 |
Attorney, Agent or Firm:
Katsuto Momii