Title:
ヒストンデアセチラーゼの新規な阻害剤としてのピペラジニル-、ピペリジニル-およびモルホリニル-誘導体
Document Type and Number:
Japanese Patent JP4674045
Kind Code:
B2
Abstract:
This invention comprises the novel compounds of formula (I) wherein t, R1, R2, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
Inventors:
Van Emmelen, Christoph
Application Number:
JP2003574655A
Publication Date:
April 20, 2011
Filing Date:
March 11, 2003
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP
International Classes:
C07D249/12; C07D401/04; A61K31/40; A61K31/438; A61K31/4427; A61K31/445; A61K31/4545; A61K31/472; A61K31/495; A61K31/496; A61K31/497; A61K31/506; A61K31/517; A61K31/53; A61K31/5377; A61K31/55; A61K31/551; A61K45/00; A61P1/04; A61P3/10; A61P5/00; A61P9/00; A61P9/02; A61P9/08; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P13/08; A61P13/10; A61P13/12; A61P15/00; A61P17/00; A61P17/04; A61P17/06; A61P17/10; A61P17/14; A61P17/16; A61P19/02; A61P19/06; A61P21/04; A61P25/00; A61P25/16; A61P25/28; A61P27/02; A61P27/06; A61P29/00; A61P31/18; A61P35/00; A61P35/02; A61P37/02; A61P37/04; A61P37/06; A61P37/08; A61P43/00; C07D207/09; C07D207/14; C07D211/26; C07D211/58; C07D213/74; C07D213/78; C07D217/02; C07D217/04; C07D239/42; C07D241/04; C07D295/14; C07D295/155; C07D295/20; C07D295/22; C07D295/26; C07D307/68; C07D317/58; C07D401/06; C07D401/12; C07D401/14; C07D403/04; C07D403/12; C07D405/12; C07D405/14; C07D409/12; C07D413/02; C07D413/04; C07D413/12; C07D471/10; C12Q1/44; C12Q1/48; G01N33/573
Domestic Patent References:
| JP63264467A | ||||
| JP5078316A |
Attorney, Agent or Firm:
Patent business corporation Odashima patent office