Title:
グラム陽性細菌のリポテイコ酸に特異的なオプソニン的かつ防御的モノクローナルおよびキメラ抗体
Document Type and Number:
Japanese Patent JP4691225
Kind Code:
B2
Abstract:
The present invention provides antibodies that bind to lipoteichoic acid of Gram Positive bacteria. These antibodies enhance phagocytosis and killing of bacteria in vivo and enhance protection from lethal infection in vivo.
Inventors:
Fischer, Gerald, W.
Schmann, Richard, F.
Won, Hin
Stinson, Jeffrey, Elle.
Schmann, Richard, F.
Won, Hin
Stinson, Jeffrey, Elle.
Application Number:
JP50463399A
Publication Date:
June 01, 2011
Filing Date:
June 16, 1998
Export Citation:
Assignee:
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Incorporated
Alter Bioscience Corporation
Alter Bioscience Corporation
International Classes:
C12N15/02; A61K39/395; A61P31/04; C07K7/00; C07K14/195; C07K16/12; C07K16/46; C12N15/09; C12P21/08; C12Q1/18; A61K38/00; A61K39/00
Domestic Patent References:
| JP7507387A |
Foreign References:
| EP0724016A1 |
Other References:
Infection and lmmunity, 1984年, vol.43, p.800-803
Infection and lmmunity, 1994年, vol.62, p.1470-143
Infection and lmmunity, 1994年, vol.62, p.1470-143
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka