Title:
縮合複素環誘導体、それを含有する医薬組成物およびその医薬用途
Document Type and Number:
Japanese Patent JP4753716
Kind Code:
B2
Abstract:
The present invention provides fused heterocyclic derivatives represented by the general formula:
wherein R 1 represents H, halogen, OH, etc.; R 2 represents H, halogen or an alkyl group; R 3 and R 4 represent H, OH, halogen, etc.; Q represents alkylene, etc.; ring A represents aryl or heteroaryl; and G represents
or
or pharmaceutically acceptable salts thereof, or prodrugs thereof, which exhibit an excellent inhibitory activity in human SGLT and are useful as agents for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, postprandial hyperglycemia, impaired glucose tolerance, diabetic complications or obesity, pharmaceutical compositions comprising the same, and pharmaceutical uses thereof.
Inventors:
Nobuhiko Fushimi
Shigeru Yonekubo
Hideyuki Muranaka
Hiroaki Shiobara
Hiroshi Teranishi
Kazuo Shimizu
Fumiaki Ito
Masayuki Isaji
Shigeru Yonekubo
Hideyuki Muranaka
Hiroaki Shiobara
Hiroshi Teranishi
Kazuo Shimizu
Fumiaki Ito
Masayuki Isaji
Application Number:
JP2005504177A
Publication Date:
August 24, 2011
Filing Date:
March 24, 2004
Export Citation:
Assignee:
Kissei Pharmaceutical Co., Ltd.
International Classes:
C07H17/00; A61K31/7036; A61K31/7042; A61K31/7048; A61K31/7056; A61K31/706; A61K45/00; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P7/10; A61P9/04; A61P9/10; A61P9/12; A61P19/06; A61P43/00; C07H15/203; C07H17/02; C07H17/04
Foreign References:
| WO2003011880A1 | 2003-02-13 | |||
| WO2002080936A1 | 2002-10-17 | |||
| WO2002098893A1 | 2002-12-12 | |||
| WO2002088157A1 | 2002-11-07 | |||
| WO2001074834A1 | 2001-10-11 |