Title:
dsRNA投与による神経疾患の処置
Document Type and Number:
Japanese Patent JP4754216
Kind Code:
B2
Abstract:
The present invention relates to methods to treat neurological disorders comprising intrathecal injection of an effective amount of a double-stranded (ds) RNA into a subject in need, wherein the dsRNA inhibits the expression of a target gene and to pharmaceutical compositions useful for such treatment.
Inventors:
Gabriele Dorn
Pam Posh Ganju
Jonathan Hall
Maria Vanda Hemmings
William Leonard Wishard
Pam Posh Ganju
Jonathan Hall
Maria Vanda Hemmings
William Leonard Wishard
Application Number:
JP2004533463A
Publication Date:
August 24, 2011
Filing Date:
September 03, 2003
Export Citation:
Assignee:
Novartis Age
International Classes:
A61K31/713; A61K48/00; A61P25/00; A61P25/04; A61P25/28; C12N15/113; A61K38/00; C12N15/09
Domestic Patent References:
| JPH11504011A | 1999-04-06 | |||
| JP2002507191A | 2002-03-05 | |||
| JP2005536438A | 2005-12-02 |
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Kenji Tomita
Mina Shiga
Masayuki Nakagawa
Hiroshi Yamazaki
Kenji Tomita
Mina Shiga
Masayuki Nakagawa