Title:
腎臓疾患予防・治療剤
Document Type and Number:
Japanese Patent JP4776138
Kind Code:
B2
Abstract:
A compound having a Rho kinase inhibitory activity, such as (+)-trans-4-(1-aminoethyl)-1-(4-pyridylcarbamoyl)-cyclohexane, has a renal interstitial fibrosis inhibitory action in renal interstitial fibrosis model mice and various other actions, and therefore, is useful as an agent for the prophylaxis or treatment of renal diseases.
Inventors:
Toshiki Moriyama
Imai Enhiro
Imai Enhiro
Application Number:
JP2001572133A
Publication Date:
September 21, 2011
Filing Date:
February 28, 2001
Export Citation:
Assignee:
Mitsubishi Tanabe Pharma Corporation
International Classes:
A61K31/4409; A61K31/00; A61K31/437; A61K31/44; A61P13/12; A61P43/00; C07D213/75; C07D213/81; C07D471/04
Domestic Patent References:
| JPH05194401A | 1993-08-03 |
Attorney, Agent or Firm:
Takashima Ichi