Title:
経口製剤およびその製造方法
Document Type and Number:
Japanese Patent JP4779970
Kind Code:
B2
Abstract:
Disclosed herein are oral preparations and their production process. The oral preparations are each composed of a complex and a coating composition applied on the complex. The complex has been obtained by dispersing or dissolving a drug having an unpleasant taste and a gastric high-molecular compound in a low melting-point substance heated to and molten at its melting point or higher and granulating the resulting mixture. The coating composition is composed of an insoluble high-molecular compound and a disintegrator at a weight ratio of from 80:20 to 99:1. In the form of microparticles or the like that contain the drug having the unpleasant taste, each oral preparation according to the present invention can maintain the masking of the unpleasant taste of the drug and the release profile of the drug even under acidic conditions.
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Inventors:
Hiroshi Ikuta
Minoru Yajima
Minoru Yajima
Application Number:
JP2006514074A
Publication Date:
September 28, 2011
Filing Date:
May 25, 2005
Export Citation:
Assignee:
Taisho Pharmaceutical Co., Ltd.
International Classes:
A61K9/58; A61K9/08; A61K9/10; A61K9/16; A61K9/50; A61K31/7048; A61K47/04; A61K47/32; A61K47/34; A61K47/38; A61P31/04
Domestic Patent References:
| JP5255075A | ||||
| JP2003504324A |
Foreign References:
| WO2000018372A1 |
Attorney, Agent or Firm:
Sotori Soichi
Ono International Patent Office
Nobuo Ono
Ono International Patent Office
Nobuo Ono