Title:
ERKのインヒビターとして有用なピラゾール組成物
Document Type and Number:
Japanese Patent JP4783532
Kind Code:
B2
Abstract:
Described herein are compounds that are useful as protein kinase inhibitors having the formula: where R1-4, Q, and T are described in the specification. The compounds are useful for treating disease states in mammals that are alleviated by a protein kinase inhibitor, particularly diseases such as cancer, inflammatory disorders, restenosis, and cardiovascular disease.
Inventors:
Green, jeremy
Tsao, Chinlong
Hale, Michael
Baker, christopher
Maltese, Francois
Janecca, James
Malican, Michael
Bemis, Guy
Si, Shaolin
Stroud, Judith
Tan, Chin
Robert Machar
Tsao, Chinlong
Hale, Michael
Baker, christopher
Maltese, Francois
Janecca, James
Malican, Michael
Bemis, Guy
Si, Shaolin
Stroud, Judith
Tan, Chin
Robert Machar
Application Number:
JP2001557854A
Publication Date:
September 28, 2011
Filing Date:
February 05, 2001
Export Citation:
Assignee:
VERTEX PHARMACEUTICALS INCORPORATED
International Classes:
A61B17/00; A61F2/02; C07D403/04; A61K31/4155; A61K31/4178; A61K31/433; A61K31/437; A61K31/4439; A61K31/454; A61K31/4709; A61K31/4725; A61K31/496; A61K31/497; A61K31/506; A61K31/5377; A61K31/551; A61K45/00; A61L27/00; A61P1/00; A61P1/16; A61P1/18; A61P3/10; A61P5/00; A61P7/02; A61P9/00; A61P9/04; A61P9/10; A61P11/00; A61P13/00; A61P13/10; A61P13/12; A61P15/00; A61P17/00; A61P17/06; A61P19/00; A61P21/00; A61P25/00; A61P25/28; A61P29/00; A61P31/00; A61P31/12; A61P35/00; A61P35/02; A61P37/00; A61P37/02; A61P37/04; A61P37/06; A61P37/08; A61P43/00; C07D231/38; C07D401/14; C07D403/14; C07D405/14; C07D417/14; C07D471/04
Domestic Patent References:
| JP8183787A | ||||
| JP2002530397A |
Foreign References:
| FR2707295A1 | ||||
| WO1998052941A1 | ||||
| WO1998052937A1 | ||||
| WO1997040019A1 |
Attorney, Agent or Firm:
Hidesaku Yamamoto